Endophthalmitis Definition
Endophthalmitis is an inflammatory condition of the intraocular cavities (ie, the aqueous or vitreous humor) usually caused by infection. Noninfectious (sterile) endophthalmitis may result from various causes such as retained native lens material after an operation or from toxic agents. Panophthalmitis is inflammation of all coats of the eye including intraocular structures.
The 2 types of endophthalmitis are endogenous (ie, metastatic) and exogenous.
- Endogenous endophthalmitis results from the hematogenous spread of organisms from a distant source of infection (eg, endocarditis).
- Exogenous endophthalmitis results from direct inoculation as a complication of ocular surgery, foreign bodies, and/or blunt or penetrating ocular trauma.


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